Simultaneous Onset of Alzheimer’s Disease in a Husband and Wife in Their Mid-Fifties: What Do We Really Know About Environmental Factors?

نویسندگان

  • Ari Pelcovits
  • Rachel Marriotti
  • Jonathan Heath
  • George Perry
  • Rudy J Castellani
چکیده

INTRODUCTION Environmental factors can play a role in the pathogenesis of Alzheimer's disease. We present a case of the simultaneous onset of Alzheimer's disease in two middle aged adults. CASE PRESENTATION A married couple ages 54 year and 51-year-old female cohabiting together were diagnosed with Alzheimer's disease within the same year. The patient's both developed cognitive decline shortly after a major renovation of their property and followed a similar disease course. The diagnosis was supported by clinical presentation and tissue pathology on autopsy. CONCLUSION Environmental factors may play a role in the pathogenesis of Alzheimer's disease. Further understanding of the disease cascade is required.

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عنوان ژورنال:

دوره 9  شماره 

صفحات  -

تاریخ انتشار 2015